Preemie survival has dramatically increased over the past decades; unfortunately, disability rates have not declined, and this is primarily driven by the one organ we do not monitor – the brain. As confirmed by key opinion leaders, there is no technology that allows for continuous monitoring of the brain. This is particularly crucial in the neonatal ICU, where long term negative outcomes such as cerebral palsy and intellectual disability are driven by injuries to the brain due to the immature cardiovascular system and under-/over-treatment. 149 Medical’s device is the first non-invasive monitor that measures real-time brain hemodynamics and metabolism, second by second. It provides early actionable alerts and continuous feedback allowing for early intervention and treatment monitoring. Clinical advisors state: our device will change the standard of care by improving lives, reducing medical errors, and reducing overall healthcare costs.