Sichen Shao, Ph.D. – 2018

Sichen Shao, Ph.D. Assistant Professor Department of Cell Biology   Harvard Medical School Linkedin Globe Twitter Activation of Nonsense-mediated Decay in Genetic Diseases and Childhood Development Mutations that introduce a premature termination codon (PTC) into protein-coding transcripts cause over 10% of congenital diseases. Nonsense-mediated decay (NMD) is a dedicated cellular pathway that degrades these mRNAs […]