Wendy W.K. Mok, Ph.D. – 2020
Wendy W.K. Mok, Ph.D. Assistant Professor University of Connecticut Health Center Linkedin Globe Envelope Phone Harnessing Microbiome Constituents to Prevent Recurrent Pediatric Methicillin-Resistant Staphylococcus Aureus Infections Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent source of infections affecting premature newborns and critically-ill children. Even after initial successful treatment, over 50% of MRSA infections recur. While some […]
Michael Lodato, Ph.D. – 2020
Michael Lodato, Ph.D. Assistant Professor University of Massachusetts Medical School Linkedin Globe Envelope Twitter Single-cell Transcriptomic and Genomic Analysis of Human Ataxia Telangiectasia Neurons Many forces can damage our DNA, including environmental forces like ultraviolet light, or internally generated mutagens like hydrogen peroxide and formaldehyde, which our cells produce in small quantities every day as […]
Julie Gaither, Ph.D., M.P.H. – 2020
Julie Gaither, Ph.D., M.P.H. Assistant Professor of Pediatrics Yale School of Medicine Globe Envelope Pediatric Opioid Poisoning: Family, Home, and Community Risk Factors Nearly 10,000 children and adolescents died from opioid poisonings in the United States over the past twenty years, and for every child who died another four were poisoned severely enough to require […]
Mohsan Saeed, Ph.D. – 2020
Mohsan Saeed, Ph.D. Assistant Professor, Biochemistry Boston University School of Medicine Linkedin Globe Twitter Probing Pathomechanisms of Enterovirus D68 Infection Enterovirus D68 (EV-D68) is an emerging enterovirus that causes severe respiratory and neurologic disease in children. The virus was first isolated in California in 1962, and although it remained relatively hidden for the next several […]
Naama Kanarek, Ph.D. – 2020
Naama Kanarek, Ph.D. Assistant Professor Boston Children’s Hospital and Harvard Medical School Linkedin Globe Twitter Back to the basics of anti-folate therapy for improved cure of pediatric cancer The standard of care for pediatric blood malignancies is the metabolic drug methotrexate (MTX). MTX inhibits the activity of the essential vitamin folate, an enzymatic cofactor known […]
Naila Makhani, M.D., M.P.H. – 2020
Naila Makhani, M.D., M.P.H. Assistant Professor of Pediatrics & Neurology Yale University Linkedin Globe Twitter Novel MRI Markers to Predict Multiple Sclerosis in Children at Risk Multiple sclerosis is the most common cause of non-traumatic neurological disability in young adults. Children with multiple sclerosis have frequent clinical relapses and may become disabled at a young […]
Silvia Chiang, M.D. – 2020
Silvia Chiang, M.D. Assistant Professor of Pediatrics Rhode Island Hospital Linkedin Globe Twitter Evaluation of Post-Tuberculosis Lung Function in Adolescents Compared to the general population, adults with a history of tuberculosis are at risk of chronic fixed airflow obstruction and poor respiratory-related quality of life, even despite successful tuberculosis treatment. No pediatric studies have examined […]
Raman Bahal, M.S., Ph.D. – 2020
Raman Bahal, M.S., Ph.D. Assistant Professor of Pharmaceutics University of Connecticut Linkedin Globe Twitter Next Generation Targeting of OncomiRs for Pediatric Glioma Therapy Glioblastoma multiforme (GBM) is a common pediatric cancer in the US, causing tens of thousands of deaths each year and its incidence is on the rise. MicroRNAs (miRNAs or miRs) are small […]
Ellen Roche, Ph.D. – 2019
Ellen Roche, Ph.D. Assistant Professor Massachusetts Institute of Technology Linkedin Globe Twitter A Circulatory Support Device for Children with Univentricular Hearts and Failing Fontan Physiology A multitude of congenital heart defects result in the need for complex pediatric cardiac surgery. Pediatric patients with single ventricle heart defects undergo multiple surgeries terminating with the Fontan procedure […]
Eunjung Alice Lee, Ph.D. – 2019
Eunjung Alice Lee, Ph.D. Assistant Professor Boston Children’s Hospital Linkedin Globe Twitter Systematic Discovery and Correction of Splicing Defects caused by Retroelement Insertions The objectives of this proposal are to systematically uncover transposable element (TE) insertions as an under-explored genetic cause of childhood Mendelian diseases (Aim 1) and to characterize how the insertions influence RNA […]