Nate Jowett, M.D. – 2019
Nate Jowett, M.D. Assistant Professor of Otolaryngology, Head and Neck Surgery Harvard Medical School and Massachusetts Eye and Ear Infirmary Linkedin Globe Twitter Gene Therapy for Peripheral Nerve Repair Congenital absence or injury to peripheral nerves yields devastating consequences. The gold standard for nerve gap repair comprises nerve autografting, wherein noncritical nerves are harvested for […]
Jason Greenberg, M.D., M.H.S. – 2019
Jason Greenberg, M.D., M.H.S. Assistant Professor of Pediatrics Yale University Linkedin Globe Twitter Real-time Prediction and Intervention for Impending Acute Kidney Injury in Hospitalized Children In the absence of a single, remarkably predictive marker of acute kidney injury (AKI), there is considerable interest in developing a multivariable model to predict AKI. We will develop a […]
William Chang, M.D., Ph.D. – 2019
William Chang, M.D., Ph.D. Assistant Professor of Medicine Yale University Linkedin Globe Twitter Microvascular networks on a chip to investigate how hyperglycemia induces microangiopathy in type 1 diabetes Type 1 diabetes is a significant chronic pediatric illness that can lead to multi-organ dysfunction driven by microangiopathy. While hyperglycemia is causative, the mechanisms underlying microvascular disease progression are complex […]
Xiaolei Su, Ph.D. – 2019
Xiaolei Su, Ph.D. Assistant Professor of Cell Biology Yale Cancer Center Linkedin Globe Twitter Mechanism of Chimeric Antigen Receptor (CAR) Signaling The overall goal of my research program is to understand the molecular mechanism of chimeric antigen receptor-triggered T cell activation and to leverage this knowledge to develop new tools for improving T cell-based cancer […]
Kristopher Sarosiek, Ph.D. – 2019
Kristopher Sarosiek, Ph.D. Assistant Professor of Radiation Biology Harvard T.H. Chan School of Public Health Linkedin Globe Twitter Role of Apoptosis in Childhood Traumatic Brain Injuries: Blocking Cell Death to Improve Outcomes Traumatic brain injuries (TBIs) resulting from falls, accidents or abuse are a leading cause of death and disability in infants and children. These […]
Sarita Patil, M.D. – 2019
Sarita Patil, M.D. Instructor Massachusetts General Hospital Linkedin Globe Twitter Protective Antibodies in Immunotherapy for Peanut Allergy Food allergy is a growing public health concern, particularly in children. More than 1% of children in the United States have peanut allergy caused by allergy antibodies (IgE) putting them at risk for severe, life-threatening allergic responses to […]
Hongmei Mou, Ph.D. – 2019
Hongmei Mou, Ph.D. Assistant Professor of Pediatrics Harvard Medical School Linkedin Globe Twitter Genetic Etiology Study of Neuroendocrine Cell Hyperplasia of Infancy (NEHI) on Dish Neuroendocrine cell hyperplasia of infancy (NEHI) is a distinctive children lung disease with hyperplasia of bombesin-immunopositive neuroendocrine cells within distal bronchioles and alveolar ducts. NEHI results in significant morbidity in […]
David Martinelli, Ph.D. – 2019
David Martinelli, Ph.D. Assistant Professor University of Connecticut Linkedin Globe Twitter Establishing the C1Q-like Protein Signaling Pathway as a Novel Target for ADHD Treatments Synaptic protein dysfunction alters neuronal communication and is a likely cause of neuropsychiatric diseases, generally termed ‘synaptopathies’. Attention-deficit/hyperactivity disorder (ADHD) is a likely example of a synaptopathy, affecting 5-7% of children […]
Alisa Khan, M.D., M.P.H. – 2018
Alisa Khan, M.D., M.P.H. Instructor in Pediatrics Boston Children’s Hospital Linkedin Globe Twitter A Mobile Application to Engage Families of Hospitalized Children in Safety Reporting Over 250,000 US patients die yearly from medical errors, making errors a leading cause of death. Families of hospitalized pediatric patients are high-yield reporters of medical errors and adverse […]
Michela Frascoli, Ph.D. – 2018
Michela Frascoli, Ph.D. Instructor University of Massachusetts Medical School Linkedin Globe Twitter Identification of the Embryonic Lymphoid Progenitors of Neonatal IL-17 Producing T Cells Every year, immune-related disorders affect millions of children worldwide. The fetal immune system during pregnancy plays a central role in determining the child’s future health. In particular, immune cells that […]